 |
Player | Position | Former Team | New Team | Transaction date | Notes | |
| 1. | Sogard, Eric | 2B | SD | OAK | 1/16/10 | Part of four-player trade | |
| 2. | Phillips, Kyle | C | SD | TOR | 1/26/12 | Minor league contract | |
| 3. | Ryan, Dusty | C | DET | SD | 12/21/09 | Acquired for player to be named or cash | |
| 4. | Zaun, Gregg | C | MIL | SD | 1/19/11 | Minor league contract | |
| 5. | Gonzalez, Edgar | IF | SD | --- | --- | Signed with Yomiuri Giants | |
| 6. | Adams, Russ | OF | SD | NYM | 1/05/10 | Minor League contract | |
| 7. | Denorfia, Chris | OF | OAK | SD | 12/18/09 | Minor League contract | |
| 8. | Floyd, Cliff | OF | SD | --- | --- | Released | |
| 9. | Giles, Brian | OF | SD | LAD | 2/08/10 | Minor League contract | |
| 10. | Kotsay, Mark | OF | MIL | SD | 11/16/11 | One-year contract | |
| 11. | Macias, Drew | OF | SD | ARI | 12/04/09 | Minor League contract | |
| 12. | Hermida, Jeremy | RF | SD | CLE | 2/05/13 | Minor league contract | |
| 13. | Baek, Cha Seung | RP | SD | --- | --- | Minor League free agent | |
| 14. | Liz, Radhames | RP | BAL | SD | 11/25/09 | Claimed off waivers | |
| 15. | Moreno, Edwin | RP | SD | BOS | 1/15/10 | Minor League contract | |
| 16. | Sanchez, Duaner | RP | SD | --- | 2/22/10 | Signed with Mexico City Red Devils | |
| 17. | Marquis, Jason | SP | SD | SD | 12/03/12 | One-year contract | |
| 18. | Moseley, Dustin | SP | SD | --- | --- | Minor league free agent | |
| 19. | Ransom, Cody | SS | ARI | SD | 1/03/13 | Minor league contract | |
| 20. | Tejada, Miguel | SS | SD | SF | 12/02/10 | One-year contract | |
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