- Josh Byrnes enters his second season as executive vice president/general manager after being promoted to the role in October 2011. Byrnes joined the Padres in December 2010 as senior vice president, baseball operations, bringing with him 17 seasons of experience in Major League Baseball. 2013 marks Byrnes' 20th year in a Major League front office.
- In his first season as Padres general manager, Byrnes made immediate additions to the club, acquiring infielder Yonder Alonso, pitchers Edinson Volquez and Brad Boxberger and catcher Yasmani Grandal from the Cincinnati Reds in exchange for pitcher Mat Latos, as well as acquiring outfielder Carlos Quentin and closer Huston Street, who was named a National League All-Star in his first season with San Diego. In addition, Byrnes signaled a commitment to team continuity by extending the contracts of outfielder Cameron Maybin and pitcher Cory Luebke prior to the start of the 2012 season, as well as the contracts of Quentin and Street during the season. In total, the Padres secured the rights to 13 free agent seasons through various contracts signed in 2012. Byrnes also made several player personnel and staff moves in an effort to improve the offense, which saw an increase of 58 runs and 30 homers over 2011.
- Byrnes previously served five seasons as executive vice president and general manager of the Arizona Diamondbacks. His tenure with the D-backs was highlighted by winning the National League West in 2007 with a 90-72 (.556) record and making it to the National League Championship Series. No National League team spent more days in first place from 2007-08 than the D-backs. Additionally, no NL team in the bottom half of payrolls won more games during the 2007-08 seasons.
- He began his front office career in 1994 with the Cleveland Indians. During his time with the Indians, Byrnes contributed on multiple fronts. In 1995 and 1996, he served as advance scout (the Indians led the AL in wins both seasons). Following the 1996 season, he was named Assistant Director of Scouting. In June 1998, he was promoted to Director of Scouting.
- In the fall of 1999, Byrnes followed Dan O'Dowd to the Colorado Rockies as assistant general manager. After serving three years with the Rockies, he moved on to accept the position of assistant general manager of the Boston Red Sox, a position he held until being named the D-backs general manager in November 2005.
- While with Boston, Byrnes assisted Red Sox General Manager Theo Epstein in all Major League personnel and contractual issues, while continuing to play an active role in all scouting matters. During Byrnes' tenure as assistant general manager, the Red Sox won at least 95 games each year from 2003-05 and broke the franchise's 86-year championship drought with a World Series title in 2004.
- Originally from Washington, D.C., Byrnes attended Haverford College in Pennsylvania, where he established school career records in home runs and RBI. He and his wife, Charity, have two daughters, Avery and Darby.